The group investigates cellular event timing during division cycles by studying Caulobacter crescentus, a model bacterium that divides asymmetrically with specialized daughter cells. Previous research identified cell cycle-regulated organizers governing polar differentiation and revealed a mechanism linking transcriptional programs to cell division via NAD(H) metabolism. Current work employs genome-wide chromatin-immunoprecipitation sequencing to map the developmental transcriptional landscape and identify previously uncharacterized cell cycle genes. The team also explores how viral and bacterial transcriptional programs coordinate during bacteriophage infection, aiming to uncover fundamental principles of genetic regulation.