The laboratory focuses on understanding innate immunity's role in vaccine response and how antigen-presenting cells condition long-lasting antibody and T cell responses. The work addresses hypo-responsiveness in immunocompromised patients through translational research combining clinical studies and animal models, examining alterations in innate immune response to vaccines. Research explores vaccine technology mechanisms including adjuvants and local innate immunity. Affiliated with the Centre for Emerging Viral Diseases at Geneva University Hospitals, the lab also investigates respiratory viral infections including SARS-COV2.