The group employs in vitro and in vivo models focusing on two main areas: molecular mechanisms sustaining neuromuscular junction maintenance between motor neurons and muscle fibers, examining how deregulation of the Akt/mTORC1 pathway affects NMJ maintenance through defective synaptic gene expression; and pathomechanisms of Autophagic-Vacuolar Myopathies, investigating mTORC1's role as a key autophagy regulator and how strict autophagy balance preserves muscle homeostasis to develop therapeutic strategies for rare neuromuscular diseases.